A CLINICAL EXPERIENCE OF RIFAMPICIN SUPPOSITORY FOR THE TREATMENT OF PULMONARY TUBERCULOSIS
PURPOSE: The usefulness of a rifampicin (RFP) suppository for treatment of pulmonary tuberculosis was examined in patients who had difficulty with oral consumption of medication.
SUBJECTS AND METHODS: Among inpatients receiving first-time treatment for pulmonary tuberculosis susceptible to both isoniazid (INH) and RFP, and who underwent standard 3- or 4-drug treatments including INH and RFP, we compared the number of days required for obtaining two and three consecutive negative sputum smears and cultures, respectively, in patients who received hospital-made suppositories or standard oral RFP administration.
RESULTS: There was no significant difference between groups in the number of days required for negative cultures and smears; although the times were equivalent, there were more number of elderly patients and those in generally poor condition in the RFP suppository group than the oral intake group.
CONCLUSION: RFP suppositories may be one method for administration of standard tuberculosis treatment in patients with difficulty in oral consumption of medication.
| Medienart: |
Artikel |
|---|
| Erscheinungsjahr: |
2015 |
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| Erschienen: |
2015 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:90 |
|---|---|
| Enthalten in: |
Kekkaku : [Tuberculosis - 90(2015), 6 vom: 26. Juni, Seite 543-7 |
| Sprache: |
Japanisch |
|---|
| Beteiligte Personen: |
Tsubota, Noriyuki [VerfasserIn] |
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| Themen: |
Antibiotics, Antitubercular |
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| Anmerkungen: |
Date Completed 15.12.2015 Date Revised 22.10.2015 published: Print Citation Status MEDLINE |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM253897548 |
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| 100 | 1 | |a Tsubota, Noriyuki |e verfasserin |4 aut | |
| 245 | 1 | 2 | |a A CLINICAL EXPERIENCE OF RIFAMPICIN SUPPOSITORY FOR THE TREATMENT OF PULMONARY TUBERCULOSIS |
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| 500 | |a Date Completed 15.12.2015 | ||
| 500 | |a Date Revised 22.10.2015 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a PURPOSE: The usefulness of a rifampicin (RFP) suppository for treatment of pulmonary tuberculosis was examined in patients who had difficulty with oral consumption of medication | ||
| 520 | |a SUBJECTS AND METHODS: Among inpatients receiving first-time treatment for pulmonary tuberculosis susceptible to both isoniazid (INH) and RFP, and who underwent standard 3- or 4-drug treatments including INH and RFP, we compared the number of days required for obtaining two and three consecutive negative sputum smears and cultures, respectively, in patients who received hospital-made suppositories or standard oral RFP administration | ||
| 520 | |a RESULTS: There was no significant difference between groups in the number of days required for negative cultures and smears; although the times were equivalent, there were more number of elderly patients and those in generally poor condition in the RFP suppository group than the oral intake group | ||
| 520 | |a CONCLUSION: RFP suppositories may be one method for administration of standard tuberculosis treatment in patients with difficulty in oral consumption of medication | ||
| 650 | 4 | |a Comparative Study | |
| 650 | 4 | |a English Abstract | |
| 650 | 4 | |a Journal Article | |
| 650 | 7 | |a Antibiotics, Antitubercular |2 NLM | |
| 650 | 7 | |a Suppositories |2 NLM | |
| 650 | 7 | |a Rifampin |2 NLM | |
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| 700 | 1 | |a Tanimukai, Shigeatsu |e verfasserin |4 aut | |
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