Recent advances in the understanding of immune-mediated nephrotic syndrome : diagnostic and prognostic implications
Glomerular diseases with severe defects in glomerular permeability give rise to heavy proteinuria and can present as nephrotic syndrome. There are many different causes of the nephrotic syndrome and a renal biopsy is nearly always needed to elucidate the underlying disease. During the last decade, substantial advances have occurred in the understanding of the pathophysiological mechanisms involved in immune-mediated glomerular diseases. Here, we review the diagnostic and prognostic implications of recent progress on the understanding of membranous nephropathy, minimal change disease, focal segmental glomerulosclerosis, amyloidosis, IgA nephropathy and membranoproliferative glomerulonephritis.
Medienart: |
E-Artikel |
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Erscheinungsjahr: |
2015 |
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Erschienen: |
2015 |
Enthalten in: |
Zur Gesamtaufnahme - volume:11 |
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Enthalten in: |
Expert review of clinical immunology - 11(2015), 4 vom: 14. Apr., Seite 489-500 |
Sprache: |
Englisch |
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Beteiligte Personen: |
Timmermans, Sjoerd A M E G [VerfasserIn] |
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Links: |
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Anmerkungen: |
Date Completed 17.12.2015 Date Revised 17.03.2015 published: Print-Electronic Citation Status MEDLINE |
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doi: |
10.1586/1744666X.2015.1024659 |
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funding: |
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Förderinstitution / Projekttitel: |
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PPN (Katalog-ID): |
NLM246928069 |
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520 | |a Glomerular diseases with severe defects in glomerular permeability give rise to heavy proteinuria and can present as nephrotic syndrome. There are many different causes of the nephrotic syndrome and a renal biopsy is nearly always needed to elucidate the underlying disease. During the last decade, substantial advances have occurred in the understanding of the pathophysiological mechanisms involved in immune-mediated glomerular diseases. Here, we review the diagnostic and prognostic implications of recent progress on the understanding of membranous nephropathy, minimal change disease, focal segmental glomerulosclerosis, amyloidosis, IgA nephropathy and membranoproliferative glomerulonephritis | ||
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