Recent advances in the understanding of immune-mediated nephrotic syndrome : diagnostic and prognostic implications

Glomerular diseases with severe defects in glomerular permeability give rise to heavy proteinuria and can present as nephrotic syndrome. There are many different causes of the nephrotic syndrome and a renal biopsy is nearly always needed to elucidate the underlying disease. During the last decade, substantial advances have occurred in the understanding of the pathophysiological mechanisms involved in immune-mediated glomerular diseases. Here, we review the diagnostic and prognostic implications of recent progress on the understanding of membranous nephropathy, minimal change disease, focal segmental glomerulosclerosis, amyloidosis, IgA nephropathy and membranoproliferative glomerulonephritis.

Medienart:

E-Artikel

Erscheinungsjahr:

2015

Erschienen:

2015

Enthalten in:

Zur Gesamtaufnahme - volume:11

Enthalten in:

Expert review of clinical immunology - 11(2015), 4 vom: 14. Apr., Seite 489-500

Sprache:

Englisch

Beteiligte Personen:

Timmermans, Sjoerd A M E G [VerfasserIn]
van Paassen, Pieter [VerfasserIn]
Cohen Tervaert, Jan Willem [VerfasserIn]

Links:

Volltext

Themen:

Amyloidosis
Diagnostics
Focal segmental glomerulosclerosis
IgA nephropathy
Journal Article
Membranoproliferative glomerulonephritis
Membranous nephropathy
Minimal change disease
Nephrotic syndrome
Prognostics
Review

Anmerkungen:

Date Completed 17.12.2015

Date Revised 17.03.2015

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1586/1744666X.2015.1024659

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM246928069