Gene-therapy for malaria prevention
Copyright © 2014 Elsevier Ltd. All rights reserved..
The limited number of tools for malaria prevention and the inability to eradicate the disease have required large investments in vaccine development, as vaccines have been the only foreseeable type of immunoprophylaxis against malaria. An alternative strategy named vectored immunoprophylaxis (VIP) now would allow genetically transduced host cells to assemble and secrete antibodies that neutralize the infectivity of the malaria parasite and prevent disease.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2014 |
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| Erschienen: |
2014 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:30 |
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| Enthalten in: |
Trends in parasitology - 30(2014), 11 vom: 01. Nov., Seite 511-3 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Rodrigues, Mauricio M [VerfasserIn] |
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| Links: |
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| Themen: |
Antibodies, Protozoan |
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| Anmerkungen: |
Date Completed 09.02.2015 Date Revised 02.12.2014 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1016/j.pt.2014.09.005 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| 520 | |a The limited number of tools for malaria prevention and the inability to eradicate the disease have required large investments in vaccine development, as vaccines have been the only foreseeable type of immunoprophylaxis against malaria. An alternative strategy named vectored immunoprophylaxis (VIP) now would allow genetically transduced host cells to assemble and secrete antibodies that neutralize the infectivity of the malaria parasite and prevent disease | ||
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