A comparison study between Candida parapsilosis sepsis and Candida albicans sepsis in preterm infants

In this study, we aimed to investigate the clinical characteristics of Candida parapsilosis sepsis in preterm infants. In this retrospective analysis of the clinical data of 11 cases of Candida parapsilosis sepsis and 13 cases of C. albicans sepsis, the two groups were compared for research using one-way analysis of variance (one-way ANOVA), chi2 test, and non-conditional logistic regression analysis. Compared to the C. albicans sepsis group, the C. parapsilosis group demonstrated a significantly lower birth weight (1331.8 +/- 252.41 vs. 1721.2 +/- 589.08) and significantly longer hospital stay (69.909 +/- 20.782 vs. 38.385 +/- 19.923) (t'/t = 2.160, -3.787; p = 0.045, 0.01, respectively); the incidences of retinopathy of prematurity (ROP) (72.7% vs. 30.8%), tienam administration (72.7% vs. 23.1%), pneumothorax, and thoracic closed drainage (27.3% vs. 0) were higher (chi2 = 4.196, 5.916, 4.052; p = 0.041, 0.015, 0.044, respectively). Logistic regression analysis indicated only hospital stay and tienam administration in the regression equation (chi2 = 18.008, p = 0.000). Compared with C. albicans sepsis, an average length hospital stay and administration of tienam are the high-risk factors for C. parapsilosis sepsis. With regard to the other predisposing factors of preterm infant fungal sepsis, there were no differences between the two groups.

Medienart:

Artikel

Erscheinungsjahr:

2012

Erschienen:

2012

Enthalten in:

Zur Gesamtaufnahme - volume:54

Enthalten in:

The Turkish journal of pediatrics - 54(2012), 5 vom: 05. Sept., Seite 502-8

Sprache:

Englisch

Beteiligte Personen:

Hua, Shaodong [VerfasserIn]
Huang, Jieting [VerfasserIn]
Wu, Zhixin [VerfasserIn]
Feng, Zhichun [VerfasserIn]

Themen:

Comparative Study
Journal Article

Anmerkungen:

Date Completed 02.04.2013

Date Revised 22.02.2013

published: Print

Citation Status MEDLINE

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM22519726X