The next-generation sequencing technology : a technology review and future perspective

As one of the most powerful tools in biomedical research, DNA sequencing not only has been improving its productivity in an exponential growth rate but also been evolving into a new layout of technological territories toward engineering and physical disciplines over the past three decades. In this technical review, we look into technical characteristics of the next-gen sequencers and provide prospective insights into their future development and applications. We envisage that some of the emerging platforms are capable of supporting the $1000 genome and $100 genome goals if given a few years for technical maturation. We also suggest that scientists from China should play an active role in this campaign that will have profound impact on both scientific research and societal healthcare systems.

Medienart:

E-Artikel

Erscheinungsjahr:

2010

Erschienen:

2010

Enthalten in:

Zur Gesamtaufnahme - volume:53

Enthalten in:

Science China. Life sciences - 53(2010), 1 vom: 28. Jan., Seite 44-57

Sprache:

Englisch

Beteiligte Personen:

Zhou, XiaoGuang [VerfasserIn]
Ren, LuFeng [VerfasserIn]
Li, YunTao [VerfasserIn]
Zhang, Meng [VerfasserIn]
Yu, YuDe [VerfasserIn]
Yu, Jun [VerfasserIn]

Links:

Volltext

Themen:

9007-49-2
DNA
Journal Article
Research Support, Non-U.S. Gov't
Review

Anmerkungen:

Date Completed 02.11.2010

Date Revised 16.03.2022

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1007/s11427-010-0023-6

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM199281564