Effects of placebo interventions on gastric motility and general autonomic activity
OBJECTIVE: The study aimed to investigate placebo effects on gastric motility and to examine possible autonomic mediating mechanisms.
METHODS: Eighteen healthy volunteers received a placebo pill on three occasions together with the verbal suggestion that it would stimulate, relax, or not affect gastric activity. Electrogastrogram, electrocardiogram, and electrodermal activity recordings were conducted for 30 min prior to and following intervention.
RESULTS: Dominant frequency of the gastric slow wave decreased in the stimulant condition, and increased in the relaxant condition, the difference among conditions being significant. No differential effects of the interventions on cardiac interbeat intervals, heart rate variability, and skin conductance levels were observed.
CONCLUSION: Stomach relaxant and stimulant placebo interventions modulated gastric motility independently from changes in general autonomic activity.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2009 |
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| Erschienen: |
2009 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:66 |
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| Enthalten in: |
Journal of psychosomatic research - 66(2009), 5 vom: 01. Mai, Seite 391-8 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Meissner, Karin [VerfasserIn] |
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| Links: |
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| Themen: |
Clinical Trial |
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| Anmerkungen: |
Date Completed 15.07.2009 Date Revised 21.04.2009 published: Print Citation Status MEDLINE |
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| doi: |
10.1016/j.jpsychores.2008.09.004 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM187942528 |
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| 500 | |a Date Revised 21.04.2009 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a OBJECTIVE: The study aimed to investigate placebo effects on gastric motility and to examine possible autonomic mediating mechanisms | ||
| 520 | |a METHODS: Eighteen healthy volunteers received a placebo pill on three occasions together with the verbal suggestion that it would stimulate, relax, or not affect gastric activity. Electrogastrogram, electrocardiogram, and electrodermal activity recordings were conducted for 30 min prior to and following intervention | ||
| 520 | |a RESULTS: Dominant frequency of the gastric slow wave decreased in the stimulant condition, and increased in the relaxant condition, the difference among conditions being significant. No differential effects of the interventions on cardiac interbeat intervals, heart rate variability, and skin conductance levels were observed | ||
| 520 | |a CONCLUSION: Stomach relaxant and stimulant placebo interventions modulated gastric motility independently from changes in general autonomic activity | ||
| 650 | 4 | |a Clinical Trial | |
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Research Support, Non-U.S. Gov't | |
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