A design for automatic preparation of highly concentrated 188Re-perrhenate solutions
Rhenium-188 is extremely suitable for the radiotherapy of balloon dilation for the coronary artery restenosis. To satisfy the need of highly concentrated (188)Re-perrhenate for the clinical applications, we designed an apparatus to achieve the purpose of concentrating (188)Re-perrhenate solution. This apparatus comprised of a concentrator, a control box and a computer with an automatic control program. A column of cation-exchange resin in Ag(+) form and an anion-exchange column in series were used in the concentration procedure. More than 90% of (188)Re isotope in the original solution could be collected with 1mL of 0.9% NaCl solution added to collect the (188)Re adsorbed in the column in this final process (90.7+/-2.2%, n=15). We also found that the radiochemical purity in the final solution remained unchanged (100%). The designed process could automatically increase the quality and efficiency of the production of highly concentrated rhenium-188 solution, and could also reduce the radiation dose absorbed by the operator.
| Medienart: |
Artikel |
|---|
| Erscheinungsjahr: |
2007 |
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| Erschienen: |
2007 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:65 |
|---|---|
| Enthalten in: |
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine - 65(2007), 1 vom: 01. Jan., Seite 21-5 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Luo, Tsai-Yueh [VerfasserIn] |
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| Themen: |
7440-15-5 |
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| Anmerkungen: |
Date Completed 09.02.2007 Date Revised 10.12.2019 published: Print-Electronic Citation Status MEDLINE |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM163043159 |
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| 100 | 1 | |a Luo, Tsai-Yueh |e verfasserin |4 aut | |
| 245 | 1 | 2 | |a A design for automatic preparation of highly concentrated 188Re-perrhenate solutions |
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| 500 | |a Date Completed 09.02.2007 | ||
| 500 | |a Date Revised 10.12.2019 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Rhenium-188 is extremely suitable for the radiotherapy of balloon dilation for the coronary artery restenosis. To satisfy the need of highly concentrated (188)Re-perrhenate for the clinical applications, we designed an apparatus to achieve the purpose of concentrating (188)Re-perrhenate solution. This apparatus comprised of a concentrator, a control box and a computer with an automatic control program. A column of cation-exchange resin in Ag(+) form and an anion-exchange column in series were used in the concentration procedure. More than 90% of (188)Re isotope in the original solution could be collected with 1mL of 0.9% NaCl solution added to collect the (188)Re adsorbed in the column in this final process (90.7+/-2.2%, n=15). We also found that the radiochemical purity in the final solution remained unchanged (100%). The designed process could automatically increase the quality and efficiency of the production of highly concentrated rhenium-188 solution, and could also reduce the radiation dose absorbed by the operator | ||
| 650 | 4 | |a Evaluation Study | |
| 650 | 4 | |a Journal Article | |
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| 700 | 1 | |a Lin, Wuu-Jyh |e verfasserin |4 aut | |
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