Autoimmune optic neuropathy with anticardiolipin antibody mimicking multiple sclerosis in a child
PURPOSE: To demonstrate that autoimmune optic neuropathy (AON) may occur in the pediatric population.
DESIGN: Interventional case report.
METHODS: A 4-year-old developed four episodes of bilateral optic neuritis with mild concurrent weakness, ataxia, or dizziness; one episode of unilateral optic neuritis; and one episode of weakness over a period of 4 years.
RESULTS: Autoimmune optic neuropathy was diagnosed because of the presence of anticardiolipin antibody and an abnormal skin biopsy with thrombin and immunoreactant deposition. She was treated with corticosteroids, aspirin, and gammaglobulin. This diminished the frequency and intensity of her attacks.
CONCLUSION: This case represents the diagnosis and treatment of AON in a child.
| Medienart: |
Artikel |
|---|
| Erscheinungsjahr: |
2003 |
|---|---|
| Erschienen: |
2003 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:136 |
|---|---|
| Enthalten in: |
American journal of ophthalmology - 136(2003), 2 vom: 25. Aug., Seite 358-60 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Frohman, Larry [VerfasserIn] |
|---|
| Themen: |
Antibodies, Anticardiolipin |
|---|
| Anmerkungen: |
Date Completed 12.08.2003 Date Revised 27.06.2019 published: Print Citation Status MEDLINE |
|---|
| Förderinstitution / Projekttitel: |
|
|---|
| PPN (Katalog-ID): |
NLM126446458 |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM126446458 | ||
| 003 | DE-627 | ||
| 005 | 20231222211859.0 | ||
| 007 | tu | ||
| 008 | 231222s2003 xx ||||| 00| ||eng c | ||
| 028 | 5 | 2 | |a pubmed24n0422.xml |
| 035 | |a (DE-627)NLM126446458 | ||
| 035 | |a (NLM)12888064 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Frohman, Larry |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Autoimmune optic neuropathy with anticardiolipin antibody mimicking multiple sclerosis in a child |
| 264 | 1 | |c 2003 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ohne Hilfsmittel zu benutzen |b n |2 rdamedia | ||
| 338 | |a Band |b nc |2 rdacarrier | ||
| 500 | |a Date Completed 12.08.2003 | ||
| 500 | |a Date Revised 27.06.2019 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a PURPOSE: To demonstrate that autoimmune optic neuropathy (AON) may occur in the pediatric population | ||
| 520 | |a DESIGN: Interventional case report | ||
| 520 | |a METHODS: A 4-year-old developed four episodes of bilateral optic neuritis with mild concurrent weakness, ataxia, or dizziness; one episode of unilateral optic neuritis; and one episode of weakness over a period of 4 years | ||
| 520 | |a RESULTS: Autoimmune optic neuropathy was diagnosed because of the presence of anticardiolipin antibody and an abnormal skin biopsy with thrombin and immunoreactant deposition. She was treated with corticosteroids, aspirin, and gammaglobulin. This diminished the frequency and intensity of her attacks | ||
| 520 | |a CONCLUSION: This case represents the diagnosis and treatment of AON in a child | ||
| 650 | 4 | |a Case Reports | |
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Research Support, Non-U.S. Gov't | |
| 650 | 7 | |a Antibodies, Anticardiolipin |2 NLM | |
| 650 | 7 | |a Glucocorticoids |2 NLM | |
| 650 | 7 | |a Immunoglobulins, Intravenous |2 NLM | |
| 650 | 7 | |a Aspirin |2 NLM | |
| 650 | 7 | |a R16CO5Y76E |2 NLM | |
| 700 | 1 | |a Turbin, Roger |e verfasserin |4 aut | |
| 700 | 1 | |a Bielory, Leonard |e verfasserin |4 aut | |
| 700 | 1 | |a Wolansky, Leo |e verfasserin |4 aut | |
| 700 | 1 | |a Lambert, W Clark |e verfasserin |4 aut | |
| 700 | 1 | |a Cook, Stuart |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t American journal of ophthalmology |d 1945 |g 136(2003), 2 vom: 25. Aug., Seite 358-60 |w (DE-627)NLM000124443 |x 1879-1891 |7 nnns |
| 773 | 1 | 8 | |g volume:136 |g year:2003 |g number:2 |g day:25 |g month:08 |g pages:358-60 |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 136 |j 2003 |e 2 |b 25 |c 08 |h 358-60 | ||