Plasma lead levels in normal and lead-intoxicated children

Lead reaches tissues through the plasma, where the concentration of this ion is characteristically low. Little information exists on the mechanisms which determine the dynamics of lead in plasma. Measurement of plasma lead levels have been determined in normal and lead-intoxicated children, newborn infants, and children with sickle-cell disease. The results in all groups were remarkably similar and constant over a wide range of blood lead concentration and regardless of hematocrit. These results lend further support to the postulate that the red cell represents a repository for lead, maintaining plasma lead concentration within closely defined limits, and that methods other than an isolated measurement of plasma lead will be necessary to uncover a presumably dynamic transport system between red cell and plasma.

Medienart:

Artikel

Erscheinungsjahr:

1974

Erschienen:

1974

Enthalten in:

Zur Gesamtaufnahme - volume:84

Enthalten in:

The Journal of pediatrics - 84(1974), 1 vom: 06. Jan., Seite 45-8

Sprache:

Englisch

Beteiligte Personen:

Rosen, J F [VerfasserIn]
Zarate-Salvador, C [VerfasserIn]
Trinidad, E E [VerfasserIn]

Themen:

2P299V784P
Journal Article
Lead
Research Support, Non-U.S. Gov't

Anmerkungen:

Date Completed 25.07.2002

Date Revised 30.06.2019

published: Print

Citation Status MEDLINE

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM11988707X