Biochemical changes of plasma in paratroops after parachuting : a preliminary investigation

OBJECTIVE: To study whether physiological and psychological stresses during parachuting jumps may result in biochemical changes of plasma in parachutists.

METHOD: Differences in the levels of hormones (cortisol, growth hormone, insulin, pancreatic glucagon, endothelin, angiotonin I and II, aldosterone), activities of enzymes (superoxide dismutase, glutathione peroxidase, glutathione S transferase), levels of the free radical damage indicator malondialdehyde (MDA), tumor necrosis factor alpha (TNF-alpha), and the main heat stress protein, HSP70, in the plasma and serum were investigated in control (non-parachuting) and parachuting paratroops.

RESULT: Significantly higher levels of serum hormones such as growth hormone, insulin, angiotonin 1, renin activities, as well as MDA and plasma TNF-alpha and HSP70 were observed in the parachuting group.

CONCLUSION: Whether these changes can potentially serve as useful biomarkers to assess possible abnormal stress in parachutists and to evaluate the health condition and to select parachutists remains to be further studied.

Medienart:

Artikel

Erscheinungsjahr:

1999

Erschienen:

1999

Enthalten in:

Zur Gesamtaufnahme - volume:12

Enthalten in:

Hang tian yi xue yu yi xue gong cheng = Space medicine & medical engineering - 12(1999), 4 vom: 17. Aug., Seite 235-9

Sprache:

Englisch

Beteiligte Personen:

Wu, T C [VerfasserIn]
Xiong, Y L [VerfasserIn]
Chen, S [VerfasserIn]
Leng, S T [VerfasserIn]
Hai, T [VerfasserIn]
Tanguay, R M [VerfasserIn]

Themen:

4964P6T9RB
4Y8F71G49Q
9002-72-6
9007-92-5
Aldosterone
Angiotensins
EC 1.15.1.1
EC 2.5.1.18
EC 3.4.23.15
Endothelins
Glucagon
Glutathione Disulfide
Glutathione Transferase
Growth Hormone
HSP70 Heat-Shock Proteins
Hydrocortisone
Insulin
Journal Article
Malondialdehyde
Renin
Research Support, Non-U.S. Gov't
Superoxide Dismutase
Tumor Necrosis Factor-alpha
ULW86O013H
WI4X0X7BPJ

Anmerkungen:

Date Completed 02.04.2000

Date Revised 21.11.2013

published: Print

Citation Status MEDLINE

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM114406618