Captopril MR renography in a swine model : toward a comprehensive evaluation of renal arterial stenosis
PURPOSE: To test the feasibility of captopril magnetic resonance (MR) renography and to validate the technique in an animal model of renal arterial stenosis.
MATERIALS AND METHODS: Seven pigs with induced renal arterial stenosis were studied. MR renography was performed with a T1-weighted approach by using three-dimensional fast imaging with steady-state precession, or FISP, sequences after administration of a bolus of 0.1 mmol of gadopentetate dimeglumine per kilogram of body weight. Captopril was administered to improve the specificity.
RESULTS: The results demonstrate that differences in renographic curves and indices are observed only if an anatomically substantial stenosis, typically a diameter reduction of more than 70%, is present and captopril is administered.
CONCLUSION: In this preliminary experience in an animal model, captopril MR renography provided data consistent with expectations based on conventional renographic results.
Medienart: |
Artikel |
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Erscheinungsjahr: |
2000 |
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Erschienen: |
2000 |
Enthalten in: |
Zur Gesamtaufnahme - volume:217 |
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Enthalten in: |
Radiology - 217(2000), 3 vom: 09. Dez., Seite 813-8 |
Sprache: |
Englisch |
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Beteiligte Personen: |
Prasad, P V [VerfasserIn] |
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Themen: |
Angiotensin-Converting Enzyme Inhibitors |
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Anmerkungen: |
Date Completed 11.01.2001 Date Revised 10.12.2019 published: Print Citation Status MEDLINE |
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Förderinstitution / Projekttitel: |
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PPN (Katalog-ID): |
NLM110260767 |
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100 | 1 | |a Prasad, P V |e verfasserin |4 aut | |
245 | 1 | 0 | |a Captopril MR renography in a swine model |b toward a comprehensive evaluation of renal arterial stenosis |
264 | 1 | |c 2000 | |
336 | |a Text |b txt |2 rdacontent | ||
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500 | |a Date Completed 11.01.2001 | ||
500 | |a Date Revised 10.12.2019 | ||
500 | |a published: Print | ||
500 | |a Citation Status MEDLINE | ||
520 | |a PURPOSE: To test the feasibility of captopril magnetic resonance (MR) renography and to validate the technique in an animal model of renal arterial stenosis | ||
520 | |a MATERIALS AND METHODS: Seven pigs with induced renal arterial stenosis were studied. MR renography was performed with a T1-weighted approach by using three-dimensional fast imaging with steady-state precession, or FISP, sequences after administration of a bolus of 0.1 mmol of gadopentetate dimeglumine per kilogram of body weight. Captopril was administered to improve the specificity | ||
520 | |a RESULTS: The results demonstrate that differences in renographic curves and indices are observed only if an anatomically substantial stenosis, typically a diameter reduction of more than 70%, is present and captopril is administered | ||
520 | |a CONCLUSION: In this preliminary experience in an animal model, captopril MR renography provided data consistent with expectations based on conventional renographic results | ||
650 | 4 | |a Evaluation Study | |
650 | 4 | |a Journal Article | |
650 | 7 | |a Angiotensin-Converting Enzyme Inhibitors |2 NLM | |
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700 | 1 | |a Sundaram, C |e verfasserin |4 aut | |
700 | 1 | |a Priatna, A |e verfasserin |4 aut | |
700 | 1 | |a Li, W |e verfasserin |4 aut | |
700 | 1 | |a Edelman, R R |e verfasserin |4 aut | |
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