Chemotactic activity of human peripheral eosinophils toward leukotriene E4
We studied the chemotactic activity of isolated human peripheral eosinophils toward leukotriene (LT) E4. We obtained eosinophil suspensions by the method of CD16 negative selection. Eosinophil chemotactic activities toward platelet activating factor (PAF, 10(-6) M) and LTE4 (10(-7) M, 10(-6) M, 10(-5) M) were studied using a modified Boyden Chamber method. Eosinophils migrated significantly toward PAF and LTE4 (10(-7) M, 10(-6) M). The chemotactic activity toward LTE, was most potential at 10(-6) M. These results suggest that LTE4 is an eosinophil chemoattractant.
| Medienart: |
Artikel |
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| Erscheinungsjahr: |
1997 |
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| Erschienen: |
1997 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:46 |
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| Enthalten in: |
Arerugi = [Allergy - 46(1997), 7 vom: 26. Juli, Seite 609-11 |
| Sprache: |
Japanisch |
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| Beteiligte Personen: |
Imai, T [VerfasserIn] |
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| Themen: |
75715-89-8 |
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| Anmerkungen: |
Date Completed 02.12.1997 Date Revised 20.11.2014 published: Print Citation Status MEDLINE |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM092537383 |
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| 100 | 1 | |a Imai, T |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Chemotactic activity of human peripheral eosinophils toward leukotriene E4 |
| 264 | 1 | |c 1997 | |
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| 500 | |a Date Completed 02.12.1997 | ||
| 500 | |a Date Revised 20.11.2014 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a We studied the chemotactic activity of isolated human peripheral eosinophils toward leukotriene (LT) E4. We obtained eosinophil suspensions by the method of CD16 negative selection. Eosinophil chemotactic activities toward platelet activating factor (PAF, 10(-6) M) and LTE4 (10(-7) M, 10(-6) M, 10(-5) M) were studied using a modified Boyden Chamber method. Eosinophils migrated significantly toward PAF and LTE4 (10(-7) M, 10(-6) M). The chemotactic activity toward LTE, was most potential at 10(-6) M. These results suggest that LTE4 is an eosinophil chemoattractant | ||
| 650 | 4 | |a English Abstract | |
| 650 | 4 | |a Journal Article | |
| 650 | 7 | |a Platelet Activating Factor |2 NLM | |
| 650 | 7 | |a Leukotriene E4 |2 NLM | |
| 650 | 7 | |a 75715-89-8 |2 NLM | |
| 700 | 1 | |a Okamoto, M |e verfasserin |4 aut | |
| 700 | 1 | |a Horikoshi, S |e verfasserin |4 aut | |
| 700 | 1 | |a Sugeta, A |e verfasserin |4 aut | |
| 700 | 1 | |a Idaira, K |e verfasserin |4 aut | |
| 700 | 1 | |a Kokubu, F |e verfasserin |4 aut | |
| 700 | 1 | |a Mita, S |e verfasserin |4 aut | |
| 700 | 1 | |a Adachi, M |e verfasserin |4 aut | |
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