An orphan nuclear receptor lacking a zinc-finger DNA-binding domain : interaction with several nuclear receptors
The yeast two-hybrid screening was applied to cloning cDNAs of proteins that interact with peroxisome proliferator-activated receptor alpha (PPAR alpha). We obtained from a rat liver cDNA library a clone encoding a protein related to the ligand-binding domain of the members of nuclear hormone receptor superfamily, whereas apparently lacking the zinc-finger DNA-binding domain. This protein interacted with the activated forms of several nuclear receptors, and thus is a novel type of heterodimer-forming nuclear receptor.
| Medienart: |
Artikel |
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| Erscheinungsjahr: |
1997 |
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| Erschienen: |
1997 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:1350 |
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| Enthalten in: |
Biochimica et biophysica acta - 1350(1997), 1 vom: 03. Jan., Seite 27-32 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Masuda, N [VerfasserIn] |
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| Themen: |
Comparative Study |
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| Anmerkungen: |
Date Completed 24.02.1997 Date Revised 10.06.2019 published: Print GENBANK: D86580, D86745, D86839 Citation Status MEDLINE |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM089691385 |
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| 100 | 1 | |a Masuda, N |e verfasserin |4 aut | |
| 245 | 1 | 3 | |a An orphan nuclear receptor lacking a zinc-finger DNA-binding domain |b interaction with several nuclear receptors |
| 264 | 1 | |c 1997 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ohne Hilfsmittel zu benutzen |b n |2 rdamedia | ||
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| 500 | |a Date Completed 24.02.1997 | ||
| 500 | |a Date Revised 10.06.2019 | ||
| 500 | |a published: Print | ||
| 500 | |a GENBANK: D86580, D86745, D86839 | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a The yeast two-hybrid screening was applied to cloning cDNAs of proteins that interact with peroxisome proliferator-activated receptor alpha (PPAR alpha). We obtained from a rat liver cDNA library a clone encoding a protein related to the ligand-binding domain of the members of nuclear hormone receptor superfamily, whereas apparently lacking the zinc-finger DNA-binding domain. This protein interacted with the activated forms of several nuclear receptors, and thus is a novel type of heterodimer-forming nuclear receptor | ||
| 650 | 4 | |a Comparative Study | |
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Research Support, Non-U.S. Gov't | |
| 650 | 7 | |a DNA, Complementary |2 NLM | |
| 650 | 7 | |a DNA-Binding Proteins |2 NLM | |
| 650 | 7 | |a Receptors, Cytoplasmic and Nuclear |2 NLM | |
| 650 | 7 | |a Recombinant Proteins |2 NLM | |
| 650 | 7 | |a Transcription Factors |2 NLM | |
| 700 | 1 | |a Yasumo, H |e verfasserin |4 aut | |
| 700 | 1 | |a Tamura, T |e verfasserin |4 aut | |
| 700 | 1 | |a Hashiguchi, N |e verfasserin |4 aut | |
| 700 | 1 | |a Furusawa, T |e verfasserin |4 aut | |
| 700 | 1 | |a Tsukamoto, T |e verfasserin |4 aut | |
| 700 | 1 | |a Sadano, H |e verfasserin |4 aut | |
| 700 | 1 | |a Osumi, T |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Biochimica et biophysica acta |d 1948 |g 1350(1997), 1 vom: 03. Jan., Seite 27-32 |w (DE-627)NLM000000698 |x 0006-3002 |7 nnns |
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