Autopsy report of acute necrotizing opticomyelopathy associated with thyroid cancer
We report an autopsied case of paraneoplastic necrotizing myelopathy. The patient had bilateral blindness, quadriplegia, and dyspnea of acute onset and died without remission 7 weeks later. The severe tissue necrosis and demyelination were found in the optic chiasm and from the medulla oblongata throughout the whole length of spinal cord. A papillary carcinoma was found in the thyroid gland at autopsy. In the present case IgG, myelin basic protein and activated helper T cells were increased in the CSF at onset, suggesting a mechanism of autoimmune demyelination for the condition.
Medienart: |
Artikel |
---|
Erscheinungsjahr: |
1993 |
---|---|
Erschienen: |
1993 |
Enthalten in: |
Zur Gesamtaufnahme - volume:120 |
---|---|
Enthalten in: |
Journal of the neurological sciences - 120(1993), 1 vom: 01. Dez., Seite 29-32 |
Sprache: |
Englisch |
---|
Beteiligte Personen: |
Kuroda, Y [VerfasserIn] |
---|
Themen: |
Case Reports |
---|
Anmerkungen: |
Date Completed 22.02.1994 Date Revised 24.07.2019 published: Print Citation Status MEDLINE |
---|
Förderinstitution / Projekttitel: |
|
---|
PPN (Katalog-ID): |
NLM074834088 |
---|
LEADER | 01000naa a22002652 4500 | ||
---|---|---|---|
001 | NLM074834088 | ||
003 | DE-627 | ||
005 | 20231222023617.0 | ||
007 | tu | ||
008 | 231222s1993 xx ||||| 00| ||eng c | ||
028 | 5 | 2 | |a pubmed24n0250.xml |
035 | |a (DE-627)NLM074834088 | ||
035 | |a (NLM)7507160 | ||
040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
041 | |a eng | ||
100 | 1 | |a Kuroda, Y |e verfasserin |4 aut | |
245 | 1 | 0 | |a Autopsy report of acute necrotizing opticomyelopathy associated with thyroid cancer |
264 | 1 | |c 1993 | |
336 | |a Text |b txt |2 rdacontent | ||
337 | |a ohne Hilfsmittel zu benutzen |b n |2 rdamedia | ||
338 | |a Band |b nc |2 rdacarrier | ||
500 | |a Date Completed 22.02.1994 | ||
500 | |a Date Revised 24.07.2019 | ||
500 | |a published: Print | ||
500 | |a Citation Status MEDLINE | ||
520 | |a We report an autopsied case of paraneoplastic necrotizing myelopathy. The patient had bilateral blindness, quadriplegia, and dyspnea of acute onset and died without remission 7 weeks later. The severe tissue necrosis and demyelination were found in the optic chiasm and from the medulla oblongata throughout the whole length of spinal cord. A papillary carcinoma was found in the thyroid gland at autopsy. In the present case IgG, myelin basic protein and activated helper T cells were increased in the CSF at onset, suggesting a mechanism of autoimmune demyelination for the condition | ||
650 | 4 | |a Case Reports | |
650 | 4 | |a Journal Article | |
650 | 7 | |a Immunoglobulin G |2 NLM | |
650 | 7 | |a Myelin Basic Protein |2 NLM | |
700 | 1 | |a Miyahara, M |e verfasserin |4 aut | |
700 | 1 | |a Sakemi, T |e verfasserin |4 aut | |
700 | 1 | |a Matsui, M |e verfasserin |4 aut | |
700 | 1 | |a Ryu, T |e verfasserin |4 aut | |
700 | 1 | |a Yamaguchi, M |e verfasserin |4 aut | |
700 | 1 | |a Sasadomi, E |e verfasserin |4 aut | |
700 | 1 | |a Sugihara, H |e verfasserin |4 aut | |
773 | 0 | 8 | |i Enthalten in |t Journal of the neurological sciences |d 1964 |g 120(1993), 1 vom: 01. Dez., Seite 29-32 |w (DE-627)NLM000061956 |x 1878-5883 |7 nnns |
773 | 1 | 8 | |g volume:120 |g year:1993 |g number:1 |g day:01 |g month:12 |g pages:29-32 |
912 | |a GBV_USEFLAG_A | ||
912 | |a GBV_NLM | ||
951 | |a AR | ||
952 | |d 120 |j 1993 |e 1 |b 01 |c 12 |h 29-32 |