Ultrastructural evaluation of the rat parotid gland in the course of intoxication with lead acetate
The purpose of this study was to evaluate the ultrastructural changes in the parotid gland of rats exposed to lead. The animals were given lead acetate in drinking water, at a concentration of 50 mg/dm3 Pb for periods of 2, 4 and 6 weeks. The ultrastructural examination showed that lead especially impaired mitochondria, caused accumulation of lipid droplets in the cytoplasm of acinar cells and inhibited the process of exocytosis of secretory granules. In the most extreme cases some acinar cells were destroyed.
| Medienart: |
Artikel |
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| Erscheinungsjahr: |
1994 |
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| Erschienen: |
1994 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:39 |
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| Enthalten in: |
Roczniki Akademii Medycznej w Bialymstoku (1995) - 39(1994) vom: 28., Seite 121-9 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Szynaka, B [VerfasserIn] |
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| Themen: |
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| Anmerkungen: |
Date Completed 17.01.1996 Date Revised 14.11.2003 published: Print Citation Status MEDLINE |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM074737694 |
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| 100 | 1 | |a Szynaka, B |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Ultrastructural evaluation of the rat parotid gland in the course of intoxication with lead acetate |
| 264 | 1 | |c 1994 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ohne Hilfsmittel zu benutzen |b n |2 rdamedia | ||
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| 500 | |a Date Completed 17.01.1996 | ||
| 500 | |a Date Revised 14.11.2003 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a The purpose of this study was to evaluate the ultrastructural changes in the parotid gland of rats exposed to lead. The animals were given lead acetate in drinking water, at a concentration of 50 mg/dm3 Pb for periods of 2, 4 and 6 weeks. The ultrastructural examination showed that lead especially impaired mitochondria, caused accumulation of lipid droplets in the cytoplasm of acinar cells and inhibited the process of exocytosis of secretory granules. In the most extreme cases some acinar cells were destroyed | ||
| 650 | 4 | |a Journal Article | |
| 650 | 7 | |a Lipids |2 NLM | |
| 650 | 7 | |a Collagen |2 NLM | |
| 650 | 7 | |a 9007-34-5 |2 NLM | |
| 700 | 1 | |a Andrzejewska, A |e verfasserin |4 aut | |
| 700 | 1 | |a Stokowska, W |e verfasserin |4 aut | |
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