The effect of inhibitors of DNA and protein synthesis on the yield of chromosome aberrations in a human lymphocyte culture under gamma and neutron irradiation at different stages of the mitotic cycle. The cytogenetic effects at the G1 stage
The impact of DNA of protein synthesis inhibitors (cycloheximide or hydroxyurea with 5-fluorodeoxyuridine -HU + FUrd, respectively) on the yield of chromosome aberration induced with gamma rays (1 or 2 Gy) and neutrons (0.5 or 1 Gy) at G1-stage of mitotic cycle was studied in human lymphocytes. The both inhibitors were discovered to increase the effect of gamma radiation at nearly all periods after irradiation during 5 hours. Conversely, the decrease in the level of chromosome aberrations was observed for neutrons after action of inhibitors at the same periods.
| Medienart: |
Artikel |
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| Erscheinungsjahr: |
1995 |
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| Erschienen: |
1995 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:35 |
|---|---|
| Enthalten in: |
Radiatsionnaia biologiia, radioecologiia - 35(1995), 5 vom: 04. Sept., Seite 730-5 |
| Sprache: |
Russisch |
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| Weiterer Titel: |
Vliianie ingibitorov sinteza DNK i belka na vykhod aberratsiĭ khromosom v kul'ture limfotsov cheloveka pri gamma- i neĭtronnom obluchenii v razlichnykh stadiiakh mitoticheskogo tsikla. Tsitogeneticheskie éffekty v stadii G1 |
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| Beteiligte Personen: |
Golub, E V [VerfasserIn] |
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| Themen: |
039LU44I5M |
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| Anmerkungen: |
Date Completed 02.01.1996 Date Revised 20.10.2016 published: Print Citation Status MEDLINE |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM074657275 |
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| 100 | 1 | |a Golub, E V |e verfasserin |4 aut | |
| 245 | 1 | 4 | |a The effect of inhibitors of DNA and protein synthesis on the yield of chromosome aberrations in a human lymphocyte culture under gamma and neutron irradiation at different stages of the mitotic cycle. The cytogenetic effects at the G1 stage |
| 246 | 3 | 3 | |a Vliianie ingibitorov sinteza DNK i belka na vykhod aberratsiĭ khromosom v kul'ture limfotsov cheloveka pri gamma- i neĭtronnom obluchenii v razlichnykh stadiiakh mitoticheskogo tsikla. Tsitogeneticheskie éffekty v stadii G1 |
| 264 | 1 | |c 1995 | |
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| 500 | |a Date Completed 02.01.1996 | ||
| 500 | |a Date Revised 20.10.2016 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a The impact of DNA of protein synthesis inhibitors (cycloheximide or hydroxyurea with 5-fluorodeoxyuridine -HU + FUrd, respectively) on the yield of chromosome aberration induced with gamma rays (1 or 2 Gy) and neutrons (0.5 or 1 Gy) at G1-stage of mitotic cycle was studied in human lymphocytes. The both inhibitors were discovered to increase the effect of gamma radiation at nearly all periods after irradiation during 5 hours. Conversely, the decrease in the level of chromosome aberrations was observed for neutrons after action of inhibitors at the same periods | ||
| 650 | 4 | |a English Abstract | |
| 650 | 4 | |a Journal Article | |
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| 650 | 7 | |a Floxuridine |2 NLM | |
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| 700 | 1 | |a Sevan'kaev, A V |e verfasserin |4 aut | |
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