Beta-adrenoceptor modulation in a case of pure autonomic failure

In a patient with pure autonomic failure, exercise did not modify beta-adrenoceptor density, probably due to an insufficient increase in plasma catecholamines. Isoproterenol infusion increased the number of beta-adrenoceptor by only 17%. Since in control subjects an increased beta-adrenoceptor level was found, following both physical stress and isoproterenol infusion, we suggest that the lack of increased beta-adrenoceptor levels may contribute to the poor circulatory adjustments observed in autonomic dysfunction during activities involving the sympathetic nervous system.

Medienart:

Artikel

Erscheinungsjahr:

1992

Erschienen:

1992

Enthalten in:

Zur Gesamtaufnahme - volume:19

Enthalten in:

The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques - 19(1992), 1 vom: 15. Feb., Seite 80-3

Sprache:

Englisch

Beteiligte Personen:

Perna, S [VerfasserIn]
Leone, R [VerfasserIn]
Farace, M J [VerfasserIn]
Brescia-Morra, V [VerfasserIn]
Campanella, G [VerfasserIn]
Brevetti, G [VerfasserIn]

Themen:

Case Reports
Catecholamines
Isoproterenol
Journal Article
L628TT009W
Receptors, Adrenergic, beta

Anmerkungen:

Date Completed 20.05.1992

Date Revised 21.11.2013

published: Print

Citation Status MEDLINE

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM012951854