Value of experimental and clinical methods on the effectiveness and side effect profile of anti-arrhythmia agents
The suppression by antiarrhythmic drugs of ventricular premature beats, pairs and salvos is frequently not associated with a suppression of ventricular tachycardia or fibrillation in the same patient. The evaluation of antiarrhythmic drugs must therefore distinguish between antiectopic, anti-reentry and anti-fibrillatory efficacy. Clinical methods such as Holter monitoring and programmed electrical stimulation which only allow the validation of anti-ectopic or anti-reentry efficacy present a major problem in the evaluation of antiarrhythmic drugs. Anti-fibrillatory drug efficacy cannot be evaluated by clinical methods.
Medienart: |
Artikel |
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Erscheinungsjahr: |
1992 |
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Erschienen: |
1992 |
Enthalten in: |
Zur Gesamtaufnahme - volume:81 Suppl 4 |
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Enthalten in: |
Zeitschrift fur Kardiologie - 81 Suppl 4(1992) vom: 11., Seite 151-5 |
Sprache: |
Deutsch |
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Weiterer Titel: |
Aussagewert von experimentellen und klinischen Methoden zur Wirksamkeit und zum Nebenwirkungsprofil von Antiarrhythmika |
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Beteiligte Personen: |
Kuck, K H [VerfasserIn] |
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Themen: |
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Anmerkungen: |
Date Completed 25.03.1993 Date Revised 15.11.2006 published: Print Citation Status MEDLINE |
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Förderinstitution / Projekttitel: |
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PPN (Katalog-ID): |
NLM012644412 |
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245 | 1 | 0 | |a Value of experimental and clinical methods on the effectiveness and side effect profile of anti-arrhythmia agents |
246 | 3 | 3 | |a Aussagewert von experimentellen und klinischen Methoden zur Wirksamkeit und zum Nebenwirkungsprofil von Antiarrhythmika |
264 | 1 | |c 1992 | |
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500 | |a Date Revised 15.11.2006 | ||
500 | |a published: Print | ||
500 | |a Citation Status MEDLINE | ||
520 | |a The suppression by antiarrhythmic drugs of ventricular premature beats, pairs and salvos is frequently not associated with a suppression of ventricular tachycardia or fibrillation in the same patient. The evaluation of antiarrhythmic drugs must therefore distinguish between antiectopic, anti-reentry and anti-fibrillatory efficacy. Clinical methods such as Holter monitoring and programmed electrical stimulation which only allow the validation of anti-ectopic or anti-reentry efficacy present a major problem in the evaluation of antiarrhythmic drugs. Anti-fibrillatory drug efficacy cannot be evaluated by clinical methods | ||
650 | 4 | |a English Abstract | |
650 | 4 | |a Journal Article | |
650 | 4 | |a Review | |
650 | 7 | |a Anti-Arrhythmia Agents |2 NLM | |
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