Value of experimental and clinical methods on the effectiveness and side effect profile of anti-arrhythmia agents

The suppression by antiarrhythmic drugs of ventricular premature beats, pairs and salvos is frequently not associated with a suppression of ventricular tachycardia or fibrillation in the same patient. The evaluation of antiarrhythmic drugs must therefore distinguish between antiectopic, anti-reentry and anti-fibrillatory efficacy. Clinical methods such as Holter monitoring and programmed electrical stimulation which only allow the validation of anti-ectopic or anti-reentry efficacy present a major problem in the evaluation of antiarrhythmic drugs. Anti-fibrillatory drug efficacy cannot be evaluated by clinical methods.

Medienart:

Artikel

Erscheinungsjahr:

1992

Erschienen:

1992

Enthalten in:

Zur Gesamtaufnahme - volume:81 Suppl 4

Enthalten in:

Zeitschrift fur Kardiologie - 81 Suppl 4(1992) vom: 11., Seite 151-5

Sprache:

Deutsch

Weiterer Titel:

Aussagewert von experimentellen und klinischen Methoden zur Wirksamkeit und zum Nebenwirkungsprofil von Antiarrhythmika

Beteiligte Personen:

Kuck, K H [VerfasserIn]

Themen:

Anti-Arrhythmia Agents
English Abstract
Journal Article
Review

Anmerkungen:

Date Completed 25.03.1993

Date Revised 15.11.2006

published: Print

Citation Status MEDLINE

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM012644412