Angioimmunoblastic lymphadenopathy with cutaneous manifestations in a 13-year-old girl
We describe a 13-year-old girl with angioimmunoblastic lymphadenopathy. The patient's main symptom was a generalized pruritic maculopapular rash located mainly on the upper and lower limbs. In addition to the skin lesions, physical examination revealed enlarged cervical, axillary and inguinal lymph nodes. There were also hepatosplenomegaly and oedema of both hands. Blood examination showed elevated ESR, haemolytic anaemia, polyclonal hypergammaglobulinaemia and eosinophilia. Virus serology including HIV I and II and HTLV I was negative. Histopathological examination of a lesional skin biopsy showed superficial and deep dermal infiltrate extending into the subcutaneous tissue. The infiltrate consisted of lymphocytes, some with atypical nuclei, histiocytoid cells, and few eosinophils. There was also proliferation of dermal blood vessels. Examination of an enlarged cervical lymph node disclosed typical histopathological features of angioimmunoblastic lymphadenopathy and confirmed the diagnosis.
Medienart: |
Artikel |
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Erscheinungsjahr: |
1992 |
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Erschienen: |
1992 |
Enthalten in: |
Zur Gesamtaufnahme - volume:43 |
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Enthalten in: |
Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete - 43(1992), 11 vom: 15. Nov., Seite 728-34 |
Sprache: |
Deutsch |
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Weiterer Titel: |
Angioimmunoblastische Lymphadenopathie mit kutanen Manifestationen bei einem 13jährigen Mädchen |
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Beteiligte Personen: |
Schotte, U [VerfasserIn] |
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Themen: |
Case Reports |
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Anmerkungen: |
Date Completed 22.01.1993 Date Revised 21.11.2013 published: Print Citation Status MEDLINE |
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Förderinstitution / Projekttitel: |
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PPN (Katalog-ID): |
NLM012621269 |
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245 | 1 | 0 | |a Angioimmunoblastic lymphadenopathy with cutaneous manifestations in a 13-year-old girl |
246 | 3 | 3 | |a Angioimmunoblastische Lymphadenopathie mit kutanen Manifestationen bei einem 13jährigen Mädchen |
264 | 1 | |c 1992 | |
336 | |a Text |b txt |2 rdacontent | ||
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500 | |a Date Completed 22.01.1993 | ||
500 | |a Date Revised 21.11.2013 | ||
500 | |a published: Print | ||
500 | |a Citation Status MEDLINE | ||
520 | |a We describe a 13-year-old girl with angioimmunoblastic lymphadenopathy. The patient's main symptom was a generalized pruritic maculopapular rash located mainly on the upper and lower limbs. In addition to the skin lesions, physical examination revealed enlarged cervical, axillary and inguinal lymph nodes. There were also hepatosplenomegaly and oedema of both hands. Blood examination showed elevated ESR, haemolytic anaemia, polyclonal hypergammaglobulinaemia and eosinophilia. Virus serology including HIV I and II and HTLV I was negative. Histopathological examination of a lesional skin biopsy showed superficial and deep dermal infiltrate extending into the subcutaneous tissue. The infiltrate consisted of lymphocytes, some with atypical nuclei, histiocytoid cells, and few eosinophils. There was also proliferation of dermal blood vessels. Examination of an enlarged cervical lymph node disclosed typical histopathological features of angioimmunoblastic lymphadenopathy and confirmed the diagnosis | ||
650 | 4 | |a Case Reports | |
650 | 4 | |a English Abstract | |
650 | 4 | |a Journal Article | |
650 | 7 | |a Gentamicins |2 NLM | |
650 | 7 | |a HLA-DR Antigens |2 NLM | |
650 | 7 | |a Triamcinolone Acetonide |2 NLM | |
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700 | 1 | |a Jansen, T |e verfasserin |4 aut | |
700 | 1 | |a Rübo, J |e verfasserin |4 aut | |
700 | 1 | |a Vandieken, R |e verfasserin |4 aut | |
700 | 1 | |a Goerz, G |e verfasserin |4 aut | |
700 | 1 | |a Plewig, G |e verfasserin |4 aut | |
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