Treatment of severe thrombocytopenia in systemic lupus erythematosus with intravenous gammaglobulin

Three patients with lupus with severe auto-immune thrombocytopenia were treated with high doses of intravenous gammaglobulin. In the patient with active disease a prolonged but partial response with respect to platelet counts was observed. In the two other patients who had no disease activity other than thrombocytopenia at the time of intravenous gammaglobulin treatment a minor (and only transient) increase in platelet counts was seen after treatment. No change in the state of disease activity nor in the levels of antinuclear antibodies, circulating immune complexes, nor complement C3/4 was observed in these three patients after treatment with intravenous gammaglobulin.

Medienart:

Artikel

Erscheinungsjahr:

1992

Erschienen:

1992

Enthalten in:

Zur Gesamtaufnahme - volume:51

Enthalten in:

Annals of the rheumatic diseases - 51(1992), 10 vom: 15. Okt., Seite 1149-51

Sprache:

Englisch

Beteiligte Personen:

ter Borg, E J [VerfasserIn]
Kallenberg, C G [VerfasserIn]

Themen:

Gamma-Globulins
Journal Article

Anmerkungen:

Date Completed 03.12.1992

Date Revised 03.05.2019

published: Print

Citation Status MEDLINE

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM012601934