Risk factors for hepatitis C virus infection in blood donors : a case-control study
OBJECTIVE: To investigate risk factors for hepatitis C virus (HCV) infection in Sydney blood donors.
DESIGN: Blood donors confirmed to be positive for HCV antibodies were compared with blood donors with a positive result of a screening assay, but whose HCV antibody status had not been confirmed. A questionnaire on sexual, parenteral and other potential risk factors was administered to both groups.
SETTING: Blood Transfusion Service in Sydney.
PARTICIPANTS: The study enrolled 220 donors who had confirmed HCV infection, and 210 donors who did not.
RESULTS: The relative risk associated with injecting drug use was 63 (95% confidence interval, 19-260) when comparison was made with all other donors. Among donors who did not report injecting drug use, a significant, independent increase in risk was found in association with having had a tattoo. Among donors who did not give a history of parenteral exposure, there was a significantly greater risk in people with more than one life-time sexual partner than in those with at most one partner.
CONCLUSION: A history of injecting drug use was elicited as the most important risk factor in Sydney blood donors with antibodies to hepatitis C. Having had a tattoo, and an increased number of lifetime sexual partners were also independently associated with HCV infection.
| Medienart: |
Artikel |
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| Erscheinungsjahr: |
1992 |
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| Erschienen: |
1992 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:157 |
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| Enthalten in: |
The Medical journal of Australia - 157(1992), 4 vom: 17. Aug., Seite 227-30 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Kaldor, J M [VerfasserIn] |
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| Themen: |
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| Anmerkungen: |
Date Completed 01.12.1992 Date Revised 07.01.2021 published: Print Citation Status MEDLINE |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM012594253 |
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| 041 | |a eng | ||
| 100 | 1 | |a Kaldor, J M |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Risk factors for hepatitis C virus infection in blood donors |b a case-control study |
| 264 | 1 | |c 1992 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ohne Hilfsmittel zu benutzen |b n |2 rdamedia | ||
| 338 | |a Band |b nc |2 rdacarrier | ||
| 500 | |a Date Completed 01.12.1992 | ||
| 500 | |a Date Revised 07.01.2021 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a OBJECTIVE: To investigate risk factors for hepatitis C virus (HCV) infection in Sydney blood donors | ||
| 520 | |a DESIGN: Blood donors confirmed to be positive for HCV antibodies were compared with blood donors with a positive result of a screening assay, but whose HCV antibody status had not been confirmed. A questionnaire on sexual, parenteral and other potential risk factors was administered to both groups | ||
| 520 | |a SETTING: Blood Transfusion Service in Sydney | ||
| 520 | |a PARTICIPANTS: The study enrolled 220 donors who had confirmed HCV infection, and 210 donors who did not | ||
| 520 | |a RESULTS: The relative risk associated with injecting drug use was 63 (95% confidence interval, 19-260) when comparison was made with all other donors. Among donors who did not report injecting drug use, a significant, independent increase in risk was found in association with having had a tattoo. Among donors who did not give a history of parenteral exposure, there was a significantly greater risk in people with more than one life-time sexual partner than in those with at most one partner | ||
| 520 | |a CONCLUSION: A history of injecting drug use was elicited as the most important risk factor in Sydney blood donors with antibodies to hepatitis C. Having had a tattoo, and an increased number of lifetime sexual partners were also independently associated with HCV infection | ||
| 650 | 4 | |a Journal Article | |
| 650 | 7 | |a Hepatitis Antibodies |2 NLM | |
| 650 | 7 | |a Hepatitis C Antibodies |2 NLM | |
| 700 | 1 | |a Archer, G T |e verfasserin |4 aut | |
| 700 | 1 | |a Buring, M L |e verfasserin |4 aut | |
| 700 | 1 | |a Ismay, S L |e verfasserin |4 aut | |
| 700 | 1 | |a Kenrick, K G |e verfasserin |4 aut | |
| 700 | 1 | |a Lien, A S |e verfasserin |4 aut | |
| 700 | 1 | |a Purusothaman, K |e verfasserin |4 aut | |
| 700 | 1 | |a Tulloch, R |e verfasserin |4 aut | |
| 700 | 1 | |a Bolton, W V |e verfasserin |4 aut | |
| 700 | 1 | |a Wylie, B R |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t The Medical journal of Australia |d 1945 |g 157(1992), 4 vom: 17. Aug., Seite 227-30 |w (DE-627)NLM000007927 |x 1326-5377 |7 nnns |
| 773 | 1 | 8 | |g volume:157 |g year:1992 |g number:4 |g day:17 |g month:08 |g pages:227-30 |
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| 952 | |d 157 |j 1992 |e 4 |b 17 |c 08 |h 227-30 | ||