Placebo controlled study showing therapeutic benefit of iloprost in the treatment of Raynaud's phenomenon
Iloprost is a chemically stable analog of prostaglandin I2 showing the same properties as the naturally occurring substance, but with advantages of ease of handling and administration to patients. A double blind within patient comparison of intravenous iloprost and placebo was undertaken in 13 patients with Raynaud's phenomenon severe enough to warrant short term hospitalization for intravenous dilator therapy; thermography was used as one form of assessment. Our results, while showing improvements in frequency of Raynaud's attacks after iloprost compared with placebo, show no significant effects on other variables.
Medienart: |
Artikel |
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Erscheinungsjahr: |
1992 |
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Erschienen: |
1992 |
Enthalten in: |
Zur Gesamtaufnahme - volume:19 |
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Enthalten in: |
The Journal of rheumatology - 19(1992), 9 vom: 01. Sept., Seite 1403-6 |
Sprache: |
Englisch |
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Beteiligte Personen: |
Kyle, M V [VerfasserIn] |
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Themen: |
Clinical Trial |
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Anmerkungen: |
Date Completed 23.12.1992 Date Revised 21.11.2013 published: Print Citation Status MEDLINE |
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Förderinstitution / Projekttitel: |
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PPN (Katalog-ID): |
NLM012592218 |
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100 | 1 | |a Kyle, M V |e verfasserin |4 aut | |
245 | 1 | 0 | |a Placebo controlled study showing therapeutic benefit of iloprost in the treatment of Raynaud's phenomenon |
264 | 1 | |c 1992 | |
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500 | |a Date Completed 23.12.1992 | ||
500 | |a Date Revised 21.11.2013 | ||
500 | |a published: Print | ||
500 | |a Citation Status MEDLINE | ||
520 | |a Iloprost is a chemically stable analog of prostaglandin I2 showing the same properties as the naturally occurring substance, but with advantages of ease of handling and administration to patients. A double blind within patient comparison of intravenous iloprost and placebo was undertaken in 13 patients with Raynaud's phenomenon severe enough to warrant short term hospitalization for intravenous dilator therapy; thermography was used as one form of assessment. Our results, while showing improvements in frequency of Raynaud's attacks after iloprost compared with placebo, show no significant effects on other variables | ||
650 | 4 | |a Clinical Trial | |
650 | 4 | |a Journal Article | |
650 | 4 | |a Randomized Controlled Trial | |
650 | 7 | |a Iloprost |2 NLM | |
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700 | 1 | |a Belcher, G |e verfasserin |4 aut | |
700 | 1 | |a Hazleman, B L |e verfasserin |4 aut | |
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