Factors affecting the bluetongue virus neutralizing antibody response and the reaction between virus and antibody

A study was made of different aspects of the bluetongue virus neutralizing antibody response and the reaction between the virus and antibody. Optimum neutralization was obtained in a 2mM Tris-HCl buffer, pH 9,0, at a temperature of 4 degrees C. The reaction of virus and antibody could be demonstrated by electron microscopy in the formation of clumps which were shown to be serotype specific. It was found that both IgM and IgG antibodies can neutralize the virus, but that IgM reached its maximum level sooner after infection than IgG.

Medienart:

Artikel

Erscheinungsjahr:

1979

Erschienen:

1979

Enthalten in:

Zur Gesamtaufnahme - volume:46

Enthalten in:

The Onderstepoort journal of veterinary research - 46(1979), 2 vom: 06. Juni, Seite 111-6

Sprache:

Englisch

Beteiligte Personen:

van der Walt, N T [VerfasserIn]

Themen:

Antibodies, Viral
Immunoglobulin G
Immunoglobulin M
Journal Article

Anmerkungen:

Date Completed 20.11.1980

Date Revised 14.11.2003

published: Print

Citation Status MEDLINE

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM000464945