Effect of sodium dichloroacetate on hyperlactatemia and hyperpyruvicemia induced by phenformin in the dog
In the normal anesthetized dog a continuous perfusion of sodium dichloroacetate (30 mg/kg.h) prevents the increase in blood lactates and pyruvates as well as the lowering of the arterial pH induced by the intraduodenal administration of phenformin (30 mg/kg). Furthermore a perfusion of sodium dichloroacetate (7.5 mg/kg.mn) during 20 minutes, three hours after the administration of phenformin, tends to improve the utilization of blood lactates and pyruvates.
| Medienart: |
Artikel |
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| Erscheinungsjahr: |
1976 |
|---|---|
| Erschienen: |
1976 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:170 |
|---|---|
| Enthalten in: |
Comptes rendus des seances de la Societe de biologie et de ses filiales - 170(1976), 4 vom: 07., Seite 820-4 |
| Sprache: |
Französisch |
|---|
| Weiterer Titel: |
Effet du dichloroacétate de sodium sur l'hyperlactatémie et l'hyperpyruvicémie provoquées par la phenformine chez le chien |
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| Beteiligte Personen: |
Loubatières, A L [VerfasserIn] |
|---|
| Themen: |
Acetates |
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| Anmerkungen: |
Date Completed 24.02.1977 Date Revised 21.11.2013 published: Print Citation Status MEDLINE |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM000126357 |
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| 100 | 1 | |a Loubatières, A L |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Effect of sodium dichloroacetate on hyperlactatemia and hyperpyruvicemia induced by phenformin in the dog |
| 246 | 3 | 3 | |a Effet du dichloroacétate de sodium sur l'hyperlactatémie et l'hyperpyruvicémie provoquées par la phenformine chez le chien |
| 264 | 1 | |c 1976 | |
| 336 | |a Text |b txt |2 rdacontent | ||
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| 500 | |a Date Completed 24.02.1977 | ||
| 500 | |a Date Revised 21.11.2013 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a In the normal anesthetized dog a continuous perfusion of sodium dichloroacetate (30 mg/kg.h) prevents the increase in blood lactates and pyruvates as well as the lowering of the arterial pH induced by the intraduodenal administration of phenformin (30 mg/kg). Furthermore a perfusion of sodium dichloroacetate (7.5 mg/kg.mn) during 20 minutes, three hours after the administration of phenformin, tends to improve the utilization of blood lactates and pyruvates | ||
| 650 | 4 | |a Comparative Study | |
| 650 | 4 | |a English Abstract | |
| 650 | 4 | |a Journal Article | |
| 650 | 7 | |a Acetates |2 NLM | |
| 650 | 7 | |a Blood Glucose |2 NLM | |
| 650 | 7 | |a Lactates |2 NLM | |
| 650 | 7 | |a Pyruvates |2 NLM | |
| 650 | 7 | |a Phenformin |2 NLM | |
| 650 | 7 | |a DD5K7529CE |2 NLM | |
| 700 | 1 | |a Valette, G |e verfasserin |4 aut | |
| 700 | 1 | |a Ribes, G |e verfasserin |4 aut | |
| 700 | 1 | |a Rondot, A M |e verfasserin |4 aut | |
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