Fast neutron and x-ray induced single strand DNA breaks in cultured mammalian cells
The relative biologic effectiveness (RBE) of fast neutrons in the production of single strand DNA breaks is 1.6 as compared to that of 250 kVp x rays. Monolayers of L-929 cells were treated with dinitrophenol during irradiation to prevent the DNA strands from rejoining; the extent of DNA damage was measured by the alkaline sucrose sedimentation method. The RBE for DNA damage is essentially the same as the RBE measured by cell survival methods.
| Medienart: |
Artikel |
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| Erscheinungsjahr: |
1976 |
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| Erschienen: |
1976 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:119 |
|---|---|
| Enthalten in: |
Radiology - 119(1976), 2 vom: 05. Mai, Seite 459-61 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Moss, A J [VerfasserIn] |
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| Themen: |
57-50-1 |
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| Anmerkungen: |
Date Completed 06.07.1976 Date Revised 15.11.2006 published: Print Citation Status MEDLINE |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM000054879 |
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| 100 | 1 | |a Moss, A J |c Jr |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Fast neutron and x-ray induced single strand DNA breaks in cultured mammalian cells |
| 264 | 1 | |c 1976 | |
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| 500 | |a Date Completed 06.07.1976 | ||
| 500 | |a Date Revised 15.11.2006 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a The relative biologic effectiveness (RBE) of fast neutrons in the production of single strand DNA breaks is 1.6 as compared to that of 250 kVp x rays. Monolayers of L-929 cells were treated with dinitrophenol during irradiation to prevent the DNA strands from rejoining; the extent of DNA damage was measured by the alkaline sucrose sedimentation method. The RBE for DNA damage is essentially the same as the RBE measured by cell survival methods | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Research Support, U.S. Gov't, Non-P.H.S. | |
| 650 | 4 | |a Research Support, U.S. Gov't, P.H.S. | |
| 650 | 7 | |a DNA, Single-Stranded |2 NLM | |
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| 650 | 7 | |a 57-50-1 |2 NLM | |
| 700 | 1 | |a Baker, M L |e verfasserin |4 aut | |
| 700 | 1 | |a Prior, R M |e verfasserin |4 aut | |
| 700 | 1 | |a Erichsen, E A |e verfasserin |4 aut | |
| 700 | 1 | |a Nagle, W A |e verfasserin |4 aut | |
| 700 | 1 | |a Dalrymple, G V |e verfasserin |4 aut | |
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