Normal arterial blood gases during experimental hypertriglyceridemia in the rat

The possible effect of high concentrations of plasma triglycerides on arterial oxygen tension was investigated in rats by infusion of lymph chylomicrons or a soybean oil emulsion (Intralipid). Mean triglyceride concentrations were raised from 130 to 1454 mg/100 ml without statistically significant change in arterial oxygen tension, oxygen saturation, carbon dioxide tension, or pH. The small reduction in arterial oxygen tension, content, or saturation observed in earlier studies may have been due to inadequate stabilization of fat emulsion then available for intravenous use. The present data suggest that high concentrations of plasma triglycerides produced by infusion of chylomicrons or Intralipid do not affect arterial blood gases in the normal rat.

Medienart:

Artikel

Erscheinungsjahr:

1975

Erschienen:

1975

Enthalten in:

Zur Gesamtaufnahme - volume:35

Enthalten in:

Scandinavian journal of clinical and laboratory investigation - 35(1975), 7 vom: 11. Nov., Seite 645-8

Sprache:

Englisch

Beteiligte Personen:

Mjös, O D [VerfasserIn]
Faergeman, O [VerfasserIn]

Themen:

142M471B3J
Carbon Dioxide
Chylomicrons
Dietary Fats
Journal Article
Oxygen
Research Support, U.S. Gov't, P.H.S.
S88TT14065
Triglycerides

Anmerkungen:

Date Completed 30.03.1976

Date Revised 21.11.2013

published: Print

Citation Status MEDLINE

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM000023299