Skeleton-doped degradable mesoporous silicon nanospheres with photo-thermal enhancement effect and synthesis method
The invention belongs to the field of material chemistry, and relates to skeleton-doped degradable mesoporous silicon nanospheres with a photo-thermal enhancement effect and a synthesis method thereof. According to the synthesis method, a cationic surfactant CTAB is used, reaction residual impurities are removed through a simple and convenient hydrogen bond/electrostatic assisted co-assembly strategy, and the skeleton-doped degradable mesoporous silicon nanospheres with the photo-thermal enhancement effect are obtained after drying. The skeleton-doped degradable mesoporous silicon nanosphereswith the photo-thermal enhancement effect are prepared. The mesoporous silicon nanospheres can effectively improve the photothermal effect and intratumoral accumulation and retention effect of carbonquantum dots, can be gradually degraded in vivo, are uniform in size, good in water dispersibility and high in biocompatibility, and can be widely applied to preparation of safe and efficient tumor photothermal therapy or combined therapy products..
Medienart: |
Patent |
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Erscheinungsjahr: |
2020 |
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Erschienen: |
2020 |
Enthalten in: |
Europäisches Patentamt - (2020) vom: 01. Dez. Zur Gesamtaufnahme - year:2020 |
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Sprache: |
Englisch |
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Beteiligte Personen: |
HUANG RONGQIN [VerfasserIn] |
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Links: |
Volltext [kostenfrei] |
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Anmerkungen: |
Source: www.epo.org (no modifications made), First posted: 2020-12-01, Last update posted on www.tib.eu: 2022-08-26, Last updated: 2023-02-09 |
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Patentnummer: |
CN112007151 |
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Förderinstitution / Projekttitel: |
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PPN (Katalog-ID): |
EPA011407964 |
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520 | |a The invention belongs to the field of material chemistry, and relates to skeleton-doped degradable mesoporous silicon nanospheres with a photo-thermal enhancement effect and a synthesis method thereof. According to the synthesis method, a cationic surfactant CTAB is used, reaction residual impurities are removed through a simple and convenient hydrogen bond/electrostatic assisted co-assembly strategy, and the skeleton-doped degradable mesoporous silicon nanospheres with the photo-thermal enhancement effect are obtained after drying. The skeleton-doped degradable mesoporous silicon nanosphereswith the photo-thermal enhancement effect are prepared. The mesoporous silicon nanospheres can effectively improve the photothermal effect and intratumoral accumulation and retention effect of carbonquantum dots, can be gradually degraded in vivo, are uniform in size, good in water dispersibility and high in biocompatibility, and can be widely applied to preparation of safe and efficient tumor photothermal therapy or combined therapy products. | ||
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