SARS-CoV-2 vaccine and preparation method thereof

The invention relates to a preparation method for a vaccine capable of treating and/ or preventing SARS-CoV-2 infection or COVID-19 diseases. The core antigen of the vaccine comprises the RBD (receptor binding zone) fusion protein of the SARS-CoV-2, and a vaccine form comprises an RBD fusion protein subunit vaccine, an RBD fusion protein mRNA vaccine or an RBD fusion protein adenovirus vector vaccine. The above vaccine immunizes an organism, and immune reaction for treating and/ or preventing the SARS-CoV-2 infection can be generated so as to be used for treating and/ or preventing COVID-19. The invention also relates to an RBD fusion gene, the RBD fusion protein, a carrier, a cell, a preparation method, a treatment method or a pharmacy purpose of the SARS-CoV-2..

Medienart:

Patent

Erscheinungsjahr:

2020

Erschienen:

2020

Enthalten in:

Europäisches Patentamt - (2020) vom: 02. Juni Zur Gesamtaufnahme - year:2020

Sprache:

Englisch

Beteiligte Personen:

LI JUNQIANG [VerfasserIn]
SI WEIXUE [VerfasserIn]
CUI HAIYAN [VerfasserIn]
LI JIN [VerfasserIn]
CHAO SHOUBAI [VerfasserIn]
ZHU TAO [VerfasserIn]

Links:

Volltext [kostenfrei]

Themen:

615
A61K: Preparations for medical, dental, or toilet purposes (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms a61j0003000000;chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles a61l; soap compositions c11d)
A61P: Specific therapeutic activity of chemical compounds or medicinal preparations
Bio
C07K: Peptides (peptides containing β-lactam rings c07d;cyclic dipeptides not having in their molecule any other peptide link than those which form their ring, e.g. piperazine-2,5-diones, c07d;ergot alkaloids of the cyclic peptide type c07d0519020000; single cell proteins, enzymes c12n;genetic engineering processes for obtaining peptides c12n0015000000)
C12N: Microorganisms or enzymes; compositions thereof; propagating, preserving, or maintaining microorganisms; mutation or genetic engineering; culture media (microbiological testing media c12q0001000000)
Che

Anmerkungen:

Source: www.epo.org (no modifications made), First posted: 2020-06-02, Last update posted on www.tib.eu: 2022-04-09, Last updated: 2023-02-09

Patentnummer:

CN111217917

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

EPA005890799