BUOYANCY-ACTIVATED CELL SORTING (BACS)-COMPATIBLE ACTIVATION/TRANSDUCTION SYSTEMS AND METHODS
Disclosed herein are methods for contacting in a closed container a host liquid including target cells, microbubble reagents comprising gas-core lipid-shelled microbubbles, and one or more antibodies or other ligands that bind to cell surface molecules on the target cells, wherein the one or more antibodies or other ligands are bound to the target cells or the microbubbles, wherein the contacting under conditions to produce target cells linked to microbubbles via the one or more antibodies or other ligands and activating the target cells to generate activated target cells..
Medienart: |
Patent |
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Erscheinungsjahr: |
2019 |
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Erschienen: |
2019 |
Enthalten in: |
Europäisches Patentamt - (2019) vom: 19. Sept. Zur Gesamtaufnahme - year:2019 |
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Sprache: |
Englisch |
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Beteiligte Personen: |
COELHO PHILIP H [VerfasserIn] |
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Links: |
Volltext [kostenfrei] |
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Themen: |
Sonstige Themen: |
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Anmerkungen: |
Source: www.epo.org (no modifications made), First posted: 2019-09-19, Last update posted on www.tib.eu: 2024-04-03, Last updated: 2024-04-09 |
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Patentnummer: |
US2019282619 |
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Förderinstitution / Projekttitel: |
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PPN (Katalog-ID): |
EPA002875179 |
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520 | |a Disclosed herein are methods for contacting in a closed container a host liquid including target cells, microbubble reagents comprising gas-core lipid-shelled microbubbles, and one or more antibodies or other ligands that bind to cell surface molecules on the target cells, wherein the one or more antibodies or other ligands are bound to the target cells or the microbubbles, wherein the contacting under conditions to produce target cells linked to microbubbles via the one or more antibodies or other ligands and activating the target cells to generate activated target cells. | ||
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