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FAAH Availability in Psychiatric Disorders: A PET Study : = FAAH Availability in Psychiatric Disorders: A PET Study

This study involves in vivo examination of FAAH availability, implicated both in the pathophysiology and therapeutics of disorders including PTSD, substance use disorders (e.g., alcohol use disorder, cannabis/cannabinoid use disorder, nicotine use disorder), psychotic disorders including schizophrenia, and mood disorders. The endocannabinoid system is a neuromodulatory system that has been implicated across a wide range of psychiatric disorders and may be implicated in the regulation of mood, appetitive behaviors, sleep, and cognition. Thus, alterations in the ECS have wide ranging implications. Finally, the ECS is being explored as a novel therapeutic target for several psychiatric disorders. Additionally, the test/retest reliability of the radiotracer, [11C]MK-3168, will be studied in up to 10 healthy control individuals.

Year of Publication: 2020
Published: Bethesda (Maryland), ClinicalTrials.gov, May 27, 2020
Language: English
Full text access: Full text access (free access)
Links: Full Text (clinicaltrials.gov)
Keywords: Alcohol Use Disorder
Alcoholism > MeSH
Clinical Study Status: Not yet recruiting
Clinical Study
Clinical Trial
Disease > MeSH
Forschungsbericht
Klinische Studie
Mental Disorders > MeSH
Post Traumatic Stress Disorder
Problem Behavior > MeSH
Psychosis
Stress Disorders, Post-Traumatic > MeSH
Stress Disorders, Traumatic > MeSH
Notes: Source: ClinicalTrials.gov (no modifications made)
ClinicalTrials.gov processed this data on June 05, 2020
Last update posted on ClinicalTrials.gov: May 27, 2020
Last updated: 2020-06-08
NCT ID:
    NCT04404712

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