Clinical Epidemiology : Practice and Methods / edited by Patrick S. Parfrey, Brendan J. Barrett
On Framing the Research Question and Choosing the Appropriate Research Design -- Bias in Clinical Research -- Definitions of Bias in Clinical Research -- Research Ethics for Clinical Researchers -- Ethical, Legal, and Social Issues (ELSI) in Clinical Genetics Research -- Longitudinal Studies 1: Determinants of Risk -- Longitudinal Studies 2: Modeling Data using Multivariate Analysis -- Longitudinal Studies 3: Data Modeling using Standard Regression Models and Extensions -- Longitudinal Studies 4: Matching Strategies to Evaluate Risk -- Longitudinal Studies 5: Development of Risk Prediction Models for Patients with Chronic Disease -- Randomized Controlled Trials 1: Design -- Randomized Controlled Trials 2: Analysis -- Randomized Controlled Trials 3: Measurement and Analysis of Patient-Reported Outcomes -- Randomized Controlled Trials 4: Planning, Analysis, and Interpretation of Quality of Life Studies -- Randomized Controlled Trials 5: Biomarkers and Surrogates/Outcomes -- Randomized Controlled Trials 6: Determining the Sample Size and Power for Clinical Trials and Cohort Studies -- Randomized Controlled Trials 7: On Contamination and Estimating the Actual Treatment Effect -- Evaluation of Diagnostic Tests -- Genetic Epidemiology of Complex Phenotypes -- Qualitative Research in Clinical Epidemiology -- Evidence Based Decision Making 1: Critical Appraisal -- Evidence Based Decision Making 2: Systematic Review and Meta-Analysis -- Evidence-Based Decision Making 3: Health Technology Assessment -- Evidence-Based Decision Making 4: Clinical Practice Guidelines -- Evidence-Based Decision Making 5: Knowledge Translation and the Knowledge to Action Cycle -- Evidence-Based Decision Making 6: Administrative Databases as Secondary Data Source for Epidemiologic and Health Service Research -- Methods in Evidence-Based Decision Making 7: Health Economics in Clinical Research -- Methods in Evidence-Based Decision Making 8: A Primer for Researchers -- Changing Health-Related Behaviors 1: Patient-Oriented Research and Patient Engagement in Health Research -- Changing Health-Care Behaviors 2: On Improving the Value of Health Spending -- Changing Health-Related Behaviors 3: Lessons from Implementation Science -- Changing Health-Related Behaviors 4: Realizing Impact of Health Research through Knowledge Translation -- Changing Health-Related Behaviors 5: On Interventions to Change Physician Behaviors -- Changing Health-Related Behaviors 6: Analysis, Interpretation, and Application of Big Data..
This third edition volume expands on the previous editions with updated chapters on longitudinal studies, randomized trials, evidence-based decisions making, and a new section on changing health-related behaviors. The chapters in this book are organized into six parts: Part One focuses on framing clinical research questions and choosing a suitable design; biases that may occur in clinical research; and the ethics associated with doing conducting research on humans. Parts Two through Four discuss designs, measurements, and analysis that pertain to evaluation of risk in longitudinal studies; assessment of therapy in controlled trials; and evaluation of diagnostic tests. Part Five presents methods used in various components of evidence-based decision-making; and Part Six highlights interventions focused on changing health-related behaviors. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of various types of bias, step-by-step, readily reproducible protocols for different research designs, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, Clinical Epidemiology: Methods and Protocols, Third Edition is a valuable resource for clinicians and researchers who want to expand their works to humans and use their findings in the health system..
Medienart: |
E-Book |
---|
Erscheinungsjahr: |
2021. |
---|---|
Erschienen: |
New York, NY: Springer US ; 2021. New York, NY: Imprint: Humana ; 2021. |
Ausgabe: |
3rd ed. 2021. |
Reihe: |
Methods in Molecular Biology - 2249 |
---|
Sprache: |
Englisch |
---|
Beteiligte Personen: |
Parfrey, Patrick S. [HerausgeberIn] |
---|
Links: |
doi.org [lizenzpflichtig] |
---|
ISBN: |
---|
Themen: |
---|
Umfang: |
1 Online-Ressource(XIII, 650 p. 90 illus., 37 illus. in color.) |
---|
doi: |
10.1007/978-1-0716-1138-8 |
---|
funding: |
|
---|---|
Förderinstitution / Projekttitel: |
|
PPN (Katalog-ID): |
1756964955 |
---|
LEADER | 01000cam a22002652 4500 | ||
---|---|---|---|
001 | 1756964955 | ||
003 | DE-627 | ||
005 | 20230426114212.0 | ||
007 | cr uuu---uuuuu | ||
008 | 210503s2021 xxu|||||o 00| ||eng c | ||
020 | |a 9781071611388 |9 978-1-0716-1138-8 | ||
024 | 7 | |a 10.1007/978-1-0716-1138-8 |2 doi | |
035 | |a (DE-627)1756964955 | ||
035 | |a (DE-599)KEP063158590 | ||
035 | |a (DE-He213)978-1-0716-1138-8 | ||
035 | |a (EBP)063158590 | ||
040 | |a DE-627 |b ger |c DE-627 |e rda | ||
041 | |a eng | ||
044 | |c XD-US | ||
072 | 7 | |a MBGR |2 bicssc | |
072 | 7 | |a SCI049000 |2 bisacsh | |
245 | 1 | 0 | |a Clinical Epidemiology |b Practice and Methods |c edited by Patrick S. Parfrey, Brendan J. Barrett |
250 | |a 3rd ed. 2021. | ||
264 | 1 | |a New York, NY |b Springer US |c 2021. | |
264 | 1 | |a New York, NY |b Imprint: Humana |c 2021. | |
300 | |a 1 Online-Ressource(XIII, 650 p. 90 illus., 37 illus. in color.) | ||
336 | |a Text |b txt |2 rdacontent | ||
337 | |a Computermedien |b c |2 rdamedia | ||
338 | |a Online-Ressource |b cr |2 rdacarrier | ||
490 | 0 | |a Methods in Molecular Biology |v 2249 | |
520 | |a On Framing the Research Question and Choosing the Appropriate Research Design -- Bias in Clinical Research -- Definitions of Bias in Clinical Research -- Research Ethics for Clinical Researchers -- Ethical, Legal, and Social Issues (ELSI) in Clinical Genetics Research -- Longitudinal Studies 1: Determinants of Risk -- Longitudinal Studies 2: Modeling Data using Multivariate Analysis -- Longitudinal Studies 3: Data Modeling using Standard Regression Models and Extensions -- Longitudinal Studies 4: Matching Strategies to Evaluate Risk -- Longitudinal Studies 5: Development of Risk Prediction Models for Patients with Chronic Disease -- Randomized Controlled Trials 1: Design -- Randomized Controlled Trials 2: Analysis -- Randomized Controlled Trials 3: Measurement and Analysis of Patient-Reported Outcomes -- Randomized Controlled Trials 4: Planning, Analysis, and Interpretation of Quality of Life Studies -- Randomized Controlled Trials 5: Biomarkers and Surrogates/Outcomes -- Randomized Controlled Trials 6: Determining the Sample Size and Power for Clinical Trials and Cohort Studies -- Randomized Controlled Trials 7: On Contamination and Estimating the Actual Treatment Effect -- Evaluation of Diagnostic Tests -- Genetic Epidemiology of Complex Phenotypes -- Qualitative Research in Clinical Epidemiology -- Evidence Based Decision Making 1: Critical Appraisal -- Evidence Based Decision Making 2: Systematic Review and Meta-Analysis -- Evidence-Based Decision Making 3: Health Technology Assessment -- Evidence-Based Decision Making 4: Clinical Practice Guidelines -- Evidence-Based Decision Making 5: Knowledge Translation and the Knowledge to Action Cycle -- Evidence-Based Decision Making 6: Administrative Databases as Secondary Data Source for Epidemiologic and Health Service Research -- Methods in Evidence-Based Decision Making 7: Health Economics in Clinical Research -- Methods in Evidence-Based Decision Making 8: A Primer for Researchers -- Changing Health-Related Behaviors 1: Patient-Oriented Research and Patient Engagement in Health Research -- Changing Health-Care Behaviors 2: On Improving the Value of Health Spending -- Changing Health-Related Behaviors 3: Lessons from Implementation Science -- Changing Health-Related Behaviors 4: Realizing Impact of Health Research through Knowledge Translation -- Changing Health-Related Behaviors 5: On Interventions to Change Physician Behaviors -- Changing Health-Related Behaviors 6: Analysis, Interpretation, and Application of Big Data. | ||
520 | |a This third edition volume expands on the previous editions with updated chapters on longitudinal studies, randomized trials, evidence-based decisions making, and a new section on changing health-related behaviors. The chapters in this book are organized into six parts: Part One focuses on framing clinical research questions and choosing a suitable design; biases that may occur in clinical research; and the ethics associated with doing conducting research on humans. Parts Two through Four discuss designs, measurements, and analysis that pertain to evaluation of risk in longitudinal studies; assessment of therapy in controlled trials; and evaluation of diagnostic tests. Part Five presents methods used in various components of evidence-based decision-making; and Part Six highlights interventions focused on changing health-related behaviors. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of various types of bias, step-by-step, readily reproducible protocols for different research designs, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, Clinical Epidemiology: Methods and Protocols, Third Edition is a valuable resource for clinicians and researchers who want to expand their works to humans and use their findings in the health system. | ||
650 | 0 | |a Molecular biology. | |
650 | 0 | |a Epidemiology. | |
700 | 1 | |a Parfrey, Patrick S. |e herausgeberin |4 edt | |
700 | 1 | |a Barrett, Brendan J. |e herausgeberin |4 edt | |
776 | 1 | |z 9781071611371 | |
776 | 1 | |z 9781071611395 | |
776 | 1 | |z 9781071611401 | |
776 | 0 | 8 | |i Erscheint auch als |n Druck-Ausgabe |z 9781071611371 |
776 | 0 | 8 | |i Erscheint auch als |n Druck-Ausgabe |z 9781071611395 |
776 | 0 | 8 | |i Erscheint auch als |n Druck-Ausgabe |z 9781071611401 |
856 | 4 | 0 | |u https://doi.org/10.1007/978-1-0716-1138-8 |m X:SPRINGER |x Resolving-System |z lizenzpflichtig |
912 | |a ZDB-2-PRO |b 2021 | ||
912 | |a ZDB-2-SEB | ||
912 | |a GBV_ILN_20 | ||
912 | |a ISIL_DE-84 | ||
912 | |a SYSFLAG_1 | ||
912 | |a GBV_KXP | ||
912 | |a SSG-OLC-PHA | ||
912 | |a GBV_ILN_24 | ||
912 | |a ISIL_DE-8 | ||
912 | |a GBV_ILN_65 | ||
912 | |a ISIL_DE-3 | ||
912 | |a GBV_ILN_2001 | ||
912 | |a ISIL_DE-21 | ||
912 | |a GBV_ILN_2002 | ||
912 | |a ISIL_DE-21-123 | ||
912 | |a GBV_ILN_2010 | ||
912 | |a ISIL_DE-15 | ||
912 | |a GBV_ILN_2015 | ||
912 | |a ISIL_DE-93 | ||
912 | |a GBV_ILN_2017 | ||
912 | |a ISIL_DE-576 | ||
912 | |a GBV_ILN_2021 | ||
912 | |a ISIL_DE-289 | ||
951 | |a BO | ||
953 | |2 045F |a 611.01816 | ||
980 | |2 20 |1 01 |x 0084 |b 4467613331 |c 00 |f --%%-- |d --%%-- |e s |j --%%-- |h CATDESC_SPR-EB |k Vervielfältigungen (z.B. Kopien, Downloads) sind nur von einzelnen Kapiteln oder Seiten und nur zum eigenen wissenschaftlichen Gebrauch erlaubt. Keine Weitergabe an Dritte. Kein systematisches Downloaden durch Robots. |u CATDESC_SPR-EB |y z |z 25-01-24 | ||
980 | |2 24 |1 01 |x 0008 |b 3923940386 |c 00 |f --%%-- |d --%%-- |e s |j --%%-- |h OLR-ESPPRO |k Vervielfältigungen (z.B. Kopien, Downloads) sind nur von einzelnen Kapiteln oder Seiten und nur zum eigenen wissenschaftlichen Gebrauch erlaubt. Die Weitergabe an Dritte sowie systematisches Downloaden sind untersagt. |y z |z 05-05-21 | ||
980 | |2 65 |1 01 |x 0003 |b 3923991622 |c 03 |f --%%-- |d ebook |e --%%-- |j --%%-- |h OLR-ZDB-2-PRO |k Vervielfältigungen (z.B. Kopien, Downloads) sind nur von einzelnen Kapiteln oder Seiten und nur zum eigenen wissenschaftlichen Gebrauch erlaubt. Die Weitergabe an Dritte sowie systematisches Downloaden sind untersagt. |y k3o |z 06-05-21 | ||
980 | |2 2001 |1 01 |x DE-21 |b 3921558476 |c 00 |f --%%-- |d --%%-- |e --%%-- |j kp |y l01 |z 03-05-21 | ||
980 | |2 2002 |1 01 |x DE-21-123 |b 3921664489 |c 00 |f --%%-- |d --%%-- |e --%%-- |j n |y l01 |z 03-05-21 | ||
980 | |2 2010 |1 01 |x DE-15 |b 4208475749 |c 00 |f --%%-- |d --%%-- |e --%%-- |j n |k Elektronischer Volltext - Campuslizenz |y l01 |z 10-11-22 | ||
980 | |2 2015 |1 01 |x DE-93 |b 3921664497 |c 00 |f --%%-- |d --%%-- |e p |j --%%-- |k Campuslizenz |y l01 |z 03-05-21 | ||
980 | |2 2017 |1 01 |x DE-576 |b 3921664500 |c 00 |f --%%-- |d --%%-- |e --%%-- |j n |k Besitznachweis BSZ nur für Dateneinspielung, keine echte Lizenz vorhanden |y l01 |z 03-05-21 | ||
980 | |2 2021 |1 01 |x DE-289 |b 3921558484 |c 00 |f --%%-- |d --%%-- |e --%%-- |j k |y l01 |z 03-05-21 | ||
981 | |2 20 |1 01 |x 0084 |r https://doi.org/10.1007/978-1-0716-1138-8 | ||
981 | |2 24 |1 01 |x 0008 |r https://doi.org/10.1007/978-1-0716-1138-8 | ||
981 | |2 65 |1 01 |x 0003 |y Volltextzugang Campus |r https://doi.org/10.1007/978-1-0716-1138-8 | ||
981 | |2 2001 |1 01 |x DE-21 |r https://doi.org/10.1007/978-1-0716-1138-8 | ||
981 | |2 2002 |1 01 |x DE-21-123 |r https://doi.org/10.1007/978-1-0716-1138-8 | ||
981 | |2 2010 |1 01 |x DE-15 |y Online-Zugriff |r https://doi.org/10.1007/978-1-0716-1138-8 | ||
981 | |2 2015 |1 01 |x DE-93 |r https://doi.org/10.1007/978-1-0716-1138-8 | ||
981 | |2 2021 |1 01 |x DE-289 |r https://doi.org/10.1007/978-1-0716-1138-8 | ||
982 | |2 2001 |1 01 |x DE-21 |8 00 |s s |a eBook-Springer-Protocols | ||
982 | |2 2002 |1 01 |x DE-21-123 |8 00 |s s |a eBook-Springer-Protocols | ||
995 | |2 20 |1 01 |x 0084 |a CATDESC_SPR-EB | ||
995 | |2 24 |1 01 |x 0008 |a OLR-ESPPRO | ||
995 | |2 65 |1 01 |x 0003 |a OLR-ZDB-2-PRO |